学术2015158右心室收缩不同步

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（英文原文）RightIntraventricularDyssynchronyinIdiopathic,Heritable,andAnorexigen-InducedPulmonaryArterialHypertension

ObjectivesTheaimofthisstudywastodeterminetheprevalenceofrightintraventriculardyssynchrony,itsdeterminantsandprognosticimpactinidiopathic,heritable,andanorexigen-inducedpulmonaryarterialhypertension.

BackgroundRightventriculardyssynchronyhasbeendescribedinpulmonaryarterialhypertension,butnoevidenceisavailableonitsprognosticimpactandevolutionaftertherapy.

MethodsIn83consecutivetherapy-na?vepatients,rightventriculardyssynchronywasevaluatedby2-dimensionalspeckle-trackingechocardiographycalculatingthestandarddeviationofthetimestopeak-systolicstrainforthe4mid-basalrightventricularsegments(RV-SD4).Afterbaseline(WorldHealthOrganization[WHO]class,pulmonaryhemodynamics,6-minwalktest[6MWT]),asecondassessmentwasperformedafter12monthsorwhenclinicalworseningoccurred.

ResultsPatientswithrightventriculardyssynchrony(RV-SDms)hadadvancedWHOclass,worse6MWT,rightventricularremodeling,andhemodynamicprofile







































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